PHARMACOKINETICS & PHARMACODYNAMICS

one-chamber intravenous bolus concentration

describes the exponential decrease in plasma concentration after a single transient intravenous administration.

C(t)=DVe−(CL/V)tC(t)=\frac{D}{V}e^{-(CL/V)t}

symbols, variables and units

D:mg;V:L;CL:L/h;t:h;C:mg/L。

applicable conditions and boundaries

One chamber, instant mixing, linear elimination; used for model research, non-individual dosing recommendations.

formula source code

The following is a copyable LaTeX expression.

C(t)=\frac{D}{V}e^{-(CL/V)t}

Reference and Extended Learning

NCBI Bookshelf · Pharmacokinetics ↗

is organized according to model definition and assumptions. Please check actual conditions and original literature before engineering, research and clinical use.

pharmacokineticsPK

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Relevant scientific figures and methodological contributions

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