linear pharmacokinetic total exposure
relates dose, bioavailability, and clearance to total exposure.
symbols, variables and units
AUC: mg·h/L; F: dimensionless; D: mg; CL: L/h.
applicable conditions and boundaries
has linear time-invariant pharmacokinetics and integrates to infinity; intravenous administration F=1.
formula source code
The following is a copyable LaTeX expression.
\mathrm{AUC}_{0\to\infty}=\frac{FD}{CL}Reference and Extended Learning
NCBI Bookshelf · Pharmacokinetics ↗is organized according to model definition and assumptions. Please check actual conditions and original literature before engineering, research and clinical use.
AUCexposed