Oxford Nanopore PromethION
is a high-throughput product platform that utilizes nanopore electrical signals for long-read sequencing.
What science makes it possible The
molecules cause current changes through the pores, and the algorithm interprets the time signal as a sequence; read length, error characteristics, modification identification and sample processing are interrelated.
Understanding the product requires putting a single formula back into the system: input measurements, materials and boundary conditions are calculated by the model and then compared with actual data. Approximations at different scales cannot be unconditionally spliced, and relevant tools will indicate applicable conditions respectively.
Commercial applications and engineering boundaries
Genome assembly and structural variation studies can exploit long fragment information while still requiring quality control, coverage analysis, and independent validation.
is an independent technical interpretation based on the manufacturer's public information and does not represent the manufacturer's adoption, endorsement or sponsorship of SciAtlas. The illustrations are original illustrations of the principles of this site, not photos of the actual products. Product specifications, certifications and availability are subject to the manufacturer's current information; the relevant tools only demonstrate public simplified models.
Manufacturer’s products and official information ↗Use online tools to understand related issues
Assembly N50 L50
Continuity does not represent assembly accuracy or completeness.
DNA k-mer Counter
k≤3, up to 64 categories, reverse complementation is not incorporated.
Phred Error Probability
probability interpretation is calibrated according to the sequencing software.
Sequencing Coverage
Uniform independent short read length ideal coverage.
linked model is used for independent learning and magnitude analysis and does not copy the manufacturer's proprietary software or pass product performance certification.
People and historical contributions behind the science
The following relationships distinguish theoretical and method pioneers and industry leaders; it does not mean that these figures independently invented the product on this page.
made important contributions to protein and nucleic acid sequence analysis and won the Nobel Prize in Chemistry twice.
Claude ShannonClaude Shannonis the founder of information theory and studies the mathematical theory of information measurement, channel capacity and security systems.
Related Elements and Materials Basics
elemental portal is for understanding related materials or molecular basis and does not claim a complete materials list for a specific model.