Emax efficacy model
uses saturation response to describe the relationship between concentration and drug efficacy.
symbols, variables and units
E, E₀, E_max: efficacy unit; C, EC₅₀: same concentration unit.
applicable conditions and boundaries
Simple direct action model; hysteresis, tolerance and multiple mechanisms need to be expanded.
formula source code
The following is a copyable LaTeX expression.
E=E_0+\frac{E_{\max}C}{EC_{50}+C}Reference and Extended Learning
NCBI Bookshelf · Pharmacokinetics ↗is organized according to model definition and assumptions. Please check actual conditions and original literature before engineering, research and clinical use.
Emaxefficacy
The