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RNA Folding

Calculate minimum free energy structures and view base pairing probabilities.

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ViennaRNA nearest neighbor thermodynamic model; up to 300 nt, does not include pseudoknots; MFE structure is not the only true conformation.

RNA Folding: uses and methods

Calculate minimum free energy structures and view base pairing probabilities.

Applicable scope and calculation boundary

ViennaRNA nearest neighbor thermodynamic model; up to 300 nt, does not include pseudoknots; MFE structure is not the only true conformation.

model and reference method

ViennaRNA / Turner parameter; partition function base pairing probability.

model version: 1.0.0. The results are used for scientific research, exploration and teaching, please interpret according to the model conditions.

input parameters

RNA sequence
A/U/G/C, up to 300 nt.
temperature(°C)
Value range: 0 – 80

How to use

  1. Load the example or enter data that matches the field description.
  2. Confirm units and models, run calculations and check diagnostics.
  3. Export charts, tables or results packages and record model versions.

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FROM SCIENCE TO PRACTICE

commercial application case

Industry Application · Independent Reproduction Example

RNA candidate sequences

nucleic acid R&D team compares possible local pairing relationships between candidate sequences.

Public industry reference: ViennaRNA Package

ViennaRNA provides nucleic acid secondary structure prediction and thermodynamic analysis algorithms.

View product or organization original information

on this site

  1. input RNA sequence and temperature
  2. uses ViennaRNA to calculate MFE and pairing probability
  3. Check secondary structure and export

Deliverables

Secondary structure teaching visualization for understanding pairing constraints

needs to be checked before landing

uses the ViennaRNA thermodynamic model; does not cover the intracellular environment, protein interactions, or complete three-dimensional folding, and is not used to confirm drug candidate effectiveness。

case is compiled for public industry purposes, and the reproduction steps are independent examples of this site; it does not mean that the above-mentioned institutions use or endorse this site, nor does it cite customer benefits that have not been publicly verified. The

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