Henderson–Hasselbalch equation
estimates the ratio of weak acid to conjugate base in a buffer system.
symbols, variables and units
[A⁻],[HA]: same concentration unit; pK_a: negative logarithm of dissociation constant.
applicable conditions and boundaries
Concentration surrogate activity approximation; very dilute, high ionic strength or extreme pH require complete equilibration.
formula source code
The following is a copyable LaTeX expression.
\mathrm{pH}=\mathrm pK_a+\log_{10}\frac{[A^-]}{[HA]}Reference and Extended Learning
NCBI Bookshelf · Biochemistry ↗is organized according to model definition and assumptions. Please check actual conditions and original literature before engineering, research and clinical use.
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